Immunodeficiency and autoimmunity: companions not opposites

Autoimmunity has long been regarded as the polar opposite of immunodeficiency, but clinical and experimental evidence refute this notion. Indeed, numerous inborn or acquired immunodeficiency syndromes are characterized by the development of autoimmune complications in the setting of deficient immune...

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Bibliographic Details
Main Author: David A. Fox
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-08-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI162170