Sympatho-adrenergic mechanisms in heart failure: new insights into pathophysiology
The sympathetic nervous system is activated in the setting of heart failure (HF) to compensate for hemodynamic instability. However, acute sympathetic surge or sustained high neuronal firing rates activates β-adrenergic receptor (βAR) signaling contributing to myocardial remodeling, dysfunction and...
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| Format: | Article |
| Language: | English |
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De Gruyter
2021-10-01
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| Series: | Medical Review |
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| Online Access: | https://doi.org/10.1515/mr-2021-0007 |