Blocking Studies to Evaluate Receptor-Specific Radioligand Binding in the CAM Model by PET and MR Imaging

Blocking Studies to Evaluate Receptor-Specific Radioligand Binding in the CAM Model by PET and MR Imaging

Inhibition studies in small animals are the standard for evaluating the specificity of newly developed drugs, including radiopharmaceuticals. Recently, it has been reported that the tumor accumulation of radiotracers can be assessed in the chorioallantoic membrane (CAM) model with similar results to...

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Bibliographic Details
Main Authors: Jessica Löffler, Hendrik Herrmann, Ellen Scheidhauer, Mareike Wirth, Anne Wasserloos, Christoph Solbach, Gerhard Glatting, Ambros J. Beer, Volker Rasche, Gordon Winter
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
CAM model
HET-CAM
PSMA
chick embryo
chicken
blocking
Online Access:https://www.mdpi.com/2072-6694/14/16/3870

Internet

https://www.mdpi.com/2072-6694/14/16/3870

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