The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma

The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma

Introduction: Asthma is the most common chronic inflammatory disease of the airways. The airway epithelium is a key driver of the disease, and numerous studies have established genome-wide differences in mRNA expression between health and asthma. However, the underlying molecular mechanisms for such...

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Bibliographic Details
Main Authors: Jennifer Rynne, Elena Ortiz-Zapater, Dustin C. Bagley, Onofrio Zanin, George Doherty, Varsha Kanabar, Jon Ward, David J. Jackson, Maddy Parsons, Jody Rosenblatt, Ian M. Adcock, Rocio T. Martinez-Nunez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
airway and lung cell biology
RNA binding protein
asthma
post-transcriptional control
tristetraprolin
ZFP36L1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1241008/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1241008/full

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