Inhibition of proliferative vitreoretinopathy by a newly developed methotrexate loaded drug carrier in vitro

Inhibition of proliferative vitreoretinopathy by a newly developed methotrexate loaded drug carrier in vitro

Purpose: Repeated intravitreal injections of methotrexate for proliferative vitreoretinopathy, a rare ocular condition that can cause vision loss, have shown beneficial effects in recent clinical studies. The purpose of this study was to develop a slow-release, long-term drug carrier composed of the...

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Bibliographic Details
Main Authors: Sebastian S. Arrow, Simone C. Felis, Anna Hillenmayer, Laura D. Strehle, Susanna F. Koenig, Efstathios Vounotrypidis, Armin Wolf, Christian M. Wertheimer
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Proliferative vitreretinopathy
Retinal detachment
Slow-release drug carrier
Methotrexate
Polylactide-co-glycolide
Orphan drug
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014779

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http://www.sciencedirect.com/science/article/pii/S0753332222014779

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