Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis.

Calmodulin kinase II (CaMKII) mediates critical signaling pathways responsible for divergent functions in the heart including calcium cycling, hypertrophy and apoptosis. Dysfunction in the CaMKII signaling pathway occurs in heart disease and is associated with increased susceptibility to life-threat...

Full description

Bibliographic Details
Main Authors: Matthew D Christensen, Wen Dun, Penelope A Boyden, Mark E Anderson, Peter J Mohler, Thomas J Hund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2778128?pdf=render