Toward dual hematopoietic stem-cell transplantation and solid-organ transplantation for sickle-cell disease

Abstract: Sickle-cell disease (SCD) leads to recurrent vaso-occlusive crises, chronic end-organ damage, and resultant physical, psychological, and social disabilities. Although hematopoietic stem-cell transplantation (HSCT) is potentially curative for SCD, this procedure is associated with well-reco...

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Bibliographic Details
Main Authors: Hitomi Hosoya, Jeffrey Levine, Peter Abt, David Henry, David L. Porter, Saar Gill
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920310818