Maternal high-fat diet decreases milk endocannabinoids with sex-specific changes in the cannabinoid and dopamine signaling and food preference in rat offspring

Maternal high-fat diet decreases milk endocannabinoids with sex-specific changes in the cannabinoid and dopamine signaling and food preference in rat offspring

IntroductionMaternal high-fat (HF) diet during gestation and lactation programs obesity in rat offspring associated with sex-dependent and tissue-specific changes of the endocannabinoid system (ECS). The ECS activation induces food intake and preference for fat as well as lipogenesis. We hypothesize...

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Bibliographic Details
Main Authors: Camilla P. Dias-Rocha, Julia C. B. Costa, Yamara S. Oliveira, Larissa B. Fassarella, Juliana Woyames, Georgia C. Atella, Gustavo R. C. Santos, Henrique M. G. Pereira, Carmen C. Pazos-Moura, Mariana M. Almeida, Isis H. Trevenzoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
maternal high-fat diet
metabolic programming
breast milk
endocannabinoid system
obesity
rat development
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1087999/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1087999/full

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