Pharmacogenetics of new oral anticoagulants
The review presents modern studies the effect of genetic polymorphisms on the efficienty and safety of therapy with new oral anticoagulants. Hepatic carboxylesterase encoded by the CES1 gene and P-glycoprotein encoded by the ABCB1 gene affect dabigatran pharmacokinetics. The role of glucuronidation...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Concilium Medicum
2023-04-01
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Series: | КардиоСоматика |
Subjects: | |
Online Access: | https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/107195/pdf_2 |