Pharmacogenetics of new oral anticoagulants

The review presents modern studies the effect of genetic polymorphisms on the efficienty and safety of therapy with new oral anticoagulants. Hepatic carboxylesterase encoded by the CES1 gene and P-glycoprotein encoded by the ABCB1 gene affect dabigatran pharmacokinetics. The role of glucuronidation...

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Bibliographic Details
Main Authors: Bella A. Azimova, Konstsantin Yu. Nikolayev, Anton S. Vorobyov, Irina A. Urvantseva
Format: Article
Language:English
Published: Concilium Medicum 2023-04-01
Series:КардиоСоматика
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Online Access:https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/107195/pdf_2