Haplin power analysis: a software module for power and sample size calculations in genetic association analyses of family triads and unrelated controls

Haplin power analysis: a software module for power and sample size calculations in genetic association analyses of family triads and unrelated controls

Abstract Background Log-linear and multinomial modeling offer a flexible framework for genetic association analyses of offspring (child), parent-of-origin and maternal effects, based on genotype data from a variety of child-parent configurations. Although the calculation of statistical power or samp...

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Bibliographic Details
Main Authors: Miriam Gjerdevik, Astanand Jugessur, Øystein A. Haaland, Julia Romanowska, Rolv T. Lie, Heather J. Cordell, Håkon K. Gjessing
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Bioinformatics
Subjects:
Log-linear and multinomial models
Genome-wide association studies (GWAS)
Statistical power estimation
Sample size estimation
Haplin
EMIM
Online Access:http://link.springer.com/article/10.1186/s12859-019-2727-3

Internet

http://link.springer.com/article/10.1186/s12859-019-2727-3

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