In vitro and in silico evaluations of actinomycin X2and actinomycin D as potent anti-tuberculosis agents

In vitro and in silico evaluations of actinomycin X2and actinomycin D as potent anti-tuberculosis agents

Background Multidrug-resistant tuberculosis (MDR-TB) is one of the world’s most devastating contagious diseases and is caused by the MDR-Mycobacterium tuberculosis (MDR-Mtb) bacteria. It is therefore essential to identify novel anti-TB drug candidates and target proteins to treat MDR-TB. Here, in vi...

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Bibliographic Details
Main Authors: Kamal Ahmad Qureshi, Faizul Azam, Muhammad Qaiser Fatmi, Mahrukh Imtiaz, Dinesh Kumar Prajapati, Pankaj Kumar Rai, Mariusz Jaremko, Abdul-Hamid Emwas, Gamal Osman Elhassan
Format: Article
Language:English
Published: PeerJ Inc. 2023-03-01
Series:PeerJ
Subjects:
Actinomycin
Streptomyces
Anti-TB drug
Molecular docking
Protein kinase PknB
Online Access:https://peerj.com/articles/14502.pdf

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https://peerj.com/articles/14502.pdf

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