Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in pancreatic ductal adenocardinoma (PDAC) tumours. In this study, we characterised previously unexplored endogenous RELA-GFP dynamics in PDAC cell lines through live single-cell ima...

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Bibliographic Details
Main Authors: Francesca Butera, Julia E Sero, Lucas G Dent, Chris Bakal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/86042