Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα
The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in pancreatic ductal adenocardinoma (PDAC) tumours. In this study, we characterised previously unexplored endogenous RELA-GFP dynamics in PDAC cell lines through live single-cell ima...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/86042 |