Genomic insights into antimicrobial potential and optimization of fermentation conditions of pig-derived Bacillus subtilis BS21

Genomic insights into antimicrobial potential and optimization of fermentation conditions of pig-derived Bacillus subtilis BS21

Bacillus spp. have been widely used as probiotic supplements in animal feed as alternatives to antibiotics. In the present study, we screened a Bacillus subtilis strain named BS21 from pig feces. Antimicrobial activities, whole genome mining and UHPLC-MS/MS analysis were used to explore its antimicr...

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Bibliographic Details
Main Authors: Di Wu, Linglong Fu, Yunhe Cao, Na Dong, Defa Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Microbiology
Subjects:
Bacillus subtilis
antimicrobial activity
secondary metabolites
fermentation conditions
response surface methodology
antibiotic alternative
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1239837/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1239837/full

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