Green One-Pot Syntheses of 2-Sulfoximidoyl-3,6-dibromo Indoles Using <i>N</i>-Br Sulfoximines as Both Brominating and Sulfoximinating Reagents

Green One-Pot Syntheses of 2-Sulfoximidoyl-3,6-dibromo Indoles Using <i>N</i>-Br Sulfoximines as Both Brominating and Sulfoximinating Reagents

A green one-pot 2,3,6-trifunctionalization of <i>N</i>-alkyl/aryl indoles was achieved by adding three equivalents of <i>N</i>-Br sulfoximine to the indole solution. A variety of 2-sulfoximidoyl-3,6-dibromo indoles were prepared with 38–94% yields using <i>N</i>-B...

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Bibliographic Details
Main Authors: Xiao Yun Chen, Yaonan Tang, Xinran Xiang, Yisong Tang, Mingyang Huang, Shaojun Zheng, Cuifeng Yang
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
2,3,6-trifunctionalization of indoles
<i>N</i>-Br sulfoximines
brominating reagent
sulfoximinating reagent
Online Access:https://www.mdpi.com/1420-3049/28/8/3380

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https://www.mdpi.com/1420-3049/28/8/3380

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