Deficiency of C-reactive protein or human C-reactive protein transgenic treatment aggravates influenza A infection in mice

C-reactive protein (CRP) has been shown to be a potential candidate target in the immunotherapy of severe influenza A infection. However, it is unclear on the pathogenesis associated with CRP in influenza infections. Here, we used influenza A H1N1 CA04 to infect human CRP transgenic mice (KI), CRP k...

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Bibliographic Details
Main Authors: Zhuohan Zhang, Yongjun Gao, Li Li, Junhao Luo, Rongbao Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1028458/full