Enhancing the Bioconversion of Azelaic Acid to Its Derivatives by Response Surface Methodology

Enhancing the Bioconversion of Azelaic Acid to Its Derivatives by Response Surface Methodology

Azelaic acid (AzA) and its derivatives have been known to be effective in the treatment of acne and various cutaneous hyperpigmentary disorders. The esterification of azelaic acid with lauryl alcohol (LA) to produce dilaurylazelate using immobilized lipase B from Candida antarctica (Novozym 435) is...

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Bibliographic Details
Main Authors: Nurshafira Khairudin, Mahiran Basri, Hamid Reza Fard Masoumi, Shazwani Samson, Siti Efliza Ashari
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
azelaic acid
anti-acne
enzymatic reaction
Novozym 435
response surface methodology (RSM)
Online Access:http://www.mdpi.com/1420-3049/23/2/397

Internet

http://www.mdpi.com/1420-3049/23/2/397

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