Myrtucommulones and Related Acylphloroglucinols from Myrtaceae as a Promising Source of Multitarget SARS-CoV-2 Cycle Inhibitors

Myrtucommulones and Related Acylphloroglucinols from Myrtaceae as a Promising Source of Multitarget SARS-CoV-2 Cycle Inhibitors

The LABEXTRACT plant extract bank, featuring diverse members of the Myrtaceae family from Brazilian hot spot regions, provides a promising avenue for bioprospection. Given the pivotal roles of the Spike protein and 3CL<sup>pro</sup> and PL<sup>pro</sup> proteases in SARS-CoV-...

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Bibliographic Details
Main Authors: Simony Carvalho Mendonça, Brendo Araujo Gomes, Mariana Freire Campos, Thamirys Silva da Fonseca, Maria Eduarda Alves Esteves, Bruce Veiga Andriolo, Caio Felipe de Araujo Ribas Cheohen, Larissa Esteves Carvalho Constant, Stephany da Silva Costa, Pedro Telles Calil, Amanda Resende Tucci, Thamara Kelcya Fonseca de Oliveira, Alice dos Santos Rosa, Vivian Neuza dos Santos Ferreira, Julia Nilo Henrique Lima, Milene Dias Miranda, Luciana Jesus da Costa, Manuela Leal da Silva, Marcus Tullius Scotti, Diego Allonso, Gilda Guimarães Leitão, Suzana Guimarães Leitão
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pharmaceuticals
Subjects:
COVID-19
FRET
pseudotyped virus
PLS regression
Online Access:https://www.mdpi.com/1424-8247/17/4/436

Internet

https://www.mdpi.com/1424-8247/17/4/436

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