In Vitro and In Vivo Effect of pH-Sensitive PLGA-TPGS-Based Hybrid Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy

In Vitro and In Vivo Effect of pH-Sensitive PLGA-TPGS-Based Hybrid Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy

Doxorubicin (DOX) is an antineoplastic agent clinically employed for treating breast cancer patients. Despite its effectiveness, its inherent adverse toxic side effects often limit its clinical application. To overcome these drawbacks, lipid–polymer hybrid nanoparticles (LPNP) arise as promising nan...

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Bibliográfalaš dieđut
Váldodahkkit: Renata S. Fernandes, Raquel Gregório Arribada, Juliana O. Silva, Armando Silva-Cunha, Danyelle M. Townsend, Lucas A. M. Ferreira, André L. B. Barros
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2022-11-01
Ráidu:Pharmaceutics
Fáttát:
doxorubicin
lipid–polymer hybrid nanoparticles
TPGS
antitumor activity
pH-sensitive
α-tocopherol succinate
Liŋkkat:https://www.mdpi.com/1999-4923/14/11/2394

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https://www.mdpi.com/1999-4923/14/11/2394

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