Single-cell mapping of peripheral blood mononuclear cells reveals key transcriptomic changes favoring coronary artery lesion in IVIG-resistant Kawasaki disease

Single-cell mapping of peripheral blood mononuclear cells reveals key transcriptomic changes favoring coronary artery lesion in IVIG-resistant Kawasaki disease

Background: Intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) poses a considerable challenge to patients and their families due to its severe complications. Previous researches have highlighted the critical role of immune disorders in its pathogenesis. However, fragmented studies bas...

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Bibliographic Details
Main Authors: Yuanzheng Zheng, Yan Zhou, Di Zhu, Xing Fu, Cao Xie, Shuna Sun, Guoyou Qin, Mei Feng, Chenglong Liu, Qingtong Zhou, Fang Liu, Chen Chu, Feng Wang, Dehua Yang, Ming-Wei Wang, Yonghao Gui
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Heliyon
Subjects:
Kawasaki disease
IVIG-Resistant
Single cell RNA-Sequencing
Coronary artery lesion
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024138881

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http://www.sciencedirect.com/science/article/pii/S2405844024138881

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