NF-κB-Dependent Production of ROS and Restriction of HSV-1 Infection in U937 Monocytic Cells

NF-κB-Dependent Production of ROS and Restriction of HSV-1 Infection in U937 Monocytic Cells

Herpes simplex virus 1 (HSV-1) can infect a wide range of cell types, including cells of the adaptive and innate immunity but, normally, it completes a fully-permissive replication cycle only in epithelial or neural cells. Complex mechanisms controlling this delicate balance in immune cells and cons...

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Bibliographic Details
Main Authors: Francesca Marino-Merlo, Emanuela Papaianni, Caterina Frezza, Silvana Pedatella, Mauro De Nisco, Beatrice Macchi, Sandro Grelli, Antonio Mastino
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
HSV-1
oxidative stress
NF-κB
innate response
Online Access:https://www.mdpi.com/1999-4915/11/5/428

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https://www.mdpi.com/1999-4915/11/5/428

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