IMMUNEPOTENT CRP induces DAMPS release and ROS-dependent autophagosome formation in HeLa and MCF-7 cells

IMMUNEPOTENT CRP induces DAMPS release and ROS-dependent autophagosome formation in HeLa and MCF-7 cells

Abstract Background IMMUNEPOTENT CRP (ICRP) can be cytotoxic to cancer cell lines. However, its widespread use in cancer patients has been limited by the absence of conclusive data on the molecular mechanism of its action. Here, we evaluated the mechanism of cell death induced by ICRP in HeLa and MC...

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Bibliographic Details
Main Authors: Ana Carolina Martínez-Torres, Alejandra Reyes-Ruiz, Kenny Misael Calvillo-Rodriguez, Karla Maria Alvarez-Valadez, Ashanti C. Uscanga-Palomeque, Reyes S. Tamez-Guerra, Cristina Rodríguez-Padilla
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Cancer
Subjects:
Autophagy
DAMPs
Bovine dialyzable leukocyte extract
ROS
Immunotherapy
Transfer factor
Online Access:http://link.springer.com/article/10.1186/s12885-020-07124-5

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http://link.springer.com/article/10.1186/s12885-020-07124-5

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