Red Queen Processes Drive Positive Selection on Major Histocompatibility Complex (MHC) Genes.

Major Histocompatibility Complex (MHC) genes code for proteins involved in the incitation of the adaptive immune response in vertebrates, which is achieved through binding oligopeptides (antigens) of pathogenic origin. Across vertebrate species, substitutions of amino acids at sites responsible for...

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Bibliographic Details
Main Authors: Maciej Jan Ejsmond, Jacek Radwan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4658181?pdf=render