BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer’s disease and other disorders of lipid-rich tissues

BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer’s disease and other disorders of lipid-rich tissues

Abstract Genetic and experimental evidence suggests that Alzheimer’s disease (AD) risk alleles and genes may influence disease susceptibility by altering the transcriptional and cellular responses of macrophages, including microglia, to damage of lipid-rich tissues like the brain. Recently, sc/nRNA...

Full description

Bibliographic Details
Main Authors: Anna Podleśny-Drabiniok, Gloriia Novikova, Yiyuan Liu, Josefine Dunst, Rose Temizer, Chiara Giannarelli, Samuele Marro, Taras Kreslavsky, Edoardo Marcora, Alison Mary Goate
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46315-7

Internet

https://doi.org/10.1038/s41467-024-46315-7

Similar Items