Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet

Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet

Abstract Background Dietary high fructose (HFr) is a known metabolic disruptor contributing to development of obesity and diabetes in Western societies. Initial molecular changes from exposure to HFr on liver metabolism may be essential to understand the perturbations leading to insulin resistance a...

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Bibliographic Details
Main Authors: Laura A. Cox, Jeannie Chan, Prahlad Rao, Zeeshan Hamid, Jeremy P. Glenn, Avinash Jadhav, Vivek Das, Genesio M. Karere, Ellen Quillen, Kylie Kavanagh, Michael Olivier
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Genomics
Subjects:
High fructose diet
Integrated omics
Transcriptomics
Proteomics
Metabolomics
miRNA
Online Access:https://doi.org/10.1186/s12864-021-08166-0

Internet

https://doi.org/10.1186/s12864-021-08166-0

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