Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study.

<h4>Background</h4>Patients with chronic lymphocytic leukemia (CLL) have reduced seroconversion rates and lower binding antibody (Ab) and neutralizing antibody (NAb) titers than healthy individuals following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA vaccination. H...

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Bibliographic Details
Main Authors: Kai Qin, Kazuhito Honjo, Scott Sherrill-Mix, Weimin Liu, Regina M Stoltz, Allisa K Oman, Lucinda A Hall, Ran Li, Sarah Sterrett, Ellen R Frederick, Jeffrey R Lancaster, Mayur Narkhede, Amitkumar Mehta, Foluso J Ogunsile, Rima B Patel, Thomas J Ketas, Victor M Cruz Portillo, Albert Cupo, Benjamin M Larimer, Anju Bansal, Paul A Goepfert, Beatrice H Hahn, Randall S Davis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1004157