Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal.

Bone marrow mesenchymal stem cells (BMSCs) are capable of homing to and repair damaged myocardial tissues. Apoptosis of BMSCs in response to various pathological stimuli leads to the attenuation of healing ability of BMSCs. Plenty of evidence has shown that elevated homocysteine level is a novel ind...

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Bibliographic Details
Main Authors: Benzhi Cai, Xingda Li, Yang Wang, Yanju Liu, Fan Yang, Hongyang Chen, Kun Yin, Xueying Tan, Jiuxin Zhu, Zhenwei Pan, Baoqiu Wang, Yanjie Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646804?pdf=render