Distance covariance entropy reveals primed states and bifurcation dynamics in single-cell RNA-Seq data
Summary: Cell-fate transitions are fundamental to development and differentiation. Studying them with single-cell omic data is important to advance our understanding of the cell-fate commitment process, yet this remains challenging. Here we present a computational method called DICE, which analyzes...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-12-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222019824 |