Distance covariance entropy reveals primed states and bifurcation dynamics in single-cell RNA-Seq data

Summary: Cell-fate transitions are fundamental to development and differentiation. Studying them with single-cell omic data is important to advance our understanding of the cell-fate commitment process, yet this remains challenging. Here we present a computational method called DICE, which analyzes...

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Bibliographic Details
Main Authors: Qi Luo, Alok K. Maity, Andrew E. Teschendorff
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222019824