Expression patterns and prognostic implications of tumor-infiltrating lymphocytes dynamics in early breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis

Expression patterns and prognostic implications of tumor-infiltrating lymphocytes dynamics in early breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis

PurposeHigh levels of tumor-infiltrating lymphocytes (TILs) are associated with better outcomes in early breast cancer and higher pathological response rates to neoadjuvant chemotherapy especially in the triple-negative (TNBC) and HER2+ subtypes. However, the dynamic changes in TILs levels after neo...

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Bibliographic Details
Main Authors: Yajing Zhu, Evangelos Tzoras, Alexios Matikas, Jonas Bergh, Antonios Valachis, Ioannis Zerdes, Theodoros Foukakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
tumor-infiltrating lymphocytes (TILs)
TILs dynamics
breast cancer
biomarker
neoadjuvant treatment
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.999843/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.999843/full

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