Comparable cellular and humoral immunity upon homologous and heterologous COVID-19 vaccination regimens in kidney transplant recipients

Comparable cellular and humoral immunity upon homologous and heterologous COVID-19 vaccination regimens in kidney transplant recipients

BackgroundKidney transplant recipients (KTRs) are at high risk for a severe course of coronavirus disease 2019 (COVID-19); thus, effective vaccination is critical. However, the achievement of protective immunogenicity is hampered by immunosuppressive therapies. We assessed cellular and humoral immun...

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Bibliographic Details
Main Authors: Nina Körber, Christopher Holzmann-Littig, Gesa Wilkens, Bo-Hung Liao, Maia L. Werz, Louise Platen, Cho-Chin Cheng, Myriam Tellenbach, Verena Kappler, Viktor Lehner, Hrvoje Mijočević, Catharina Christa, Volker Assfalg, Uwe Heemann, Christoph Schmaderer, Ulrike Protzer, Matthias C. Braunisch, Tanja Bauer, Lutz Renders
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
COVID-19 vaccination
immunosuppressive therapy
kidney transplant recipients
multiplex Fluorospot
neutralizing antibodies
T-cell responses
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172477/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172477/full

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