Novel heparan sulfate-binding peptides for blocking herpesvirus entry.

Human cytomegalovirus (HCMV) infection can lead to congenital hearing loss and mental retardation. Upon immune suppression, reactivation of latent HCMV or primary infection increases morbidity in cancer, transplantation, and late stage AIDS patients. Current treatments include nucleoside analogues,...

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Bibliographic Details
Main Authors: Pranay Dogra, Emily B Martin, Angela Williams, Raphael L Richardson, James S Foster, Nicole Hackenback, Stephen J Kennel, Tim E Sparer, Jonathan S Wall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4436313?pdf=render