Accounting for cis-regulatory constraint prioritizes genes likely to affect species-specific traits
Abstract Measuring allele-specific expression in interspecies hybrids is a powerful way to detect cis-regulatory changes underlying adaptation. However, it remains difficult to identify genes most likely to explain species-specific traits. Here, we outline a simple strategy that leverages population...
Main Authors: | Alexander L. Starr, David Gokhman, Hunter B. Fraser |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-023-02846-8 |
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