Impact of β-Amyloids Induced Disruption of Ca<sup>2+</sup> Homeostasis in a Simple Model of Neuronal Activity

Alzheimer’s disease is characterized by a marked dysregulation of intracellular Ca<sup>2+</sup> homeostasis. In particular, toxic β-amyloids (Aβ) perturb the activities of numerous Ca<sup>2+</sup> transporters or channels. Because of the tight coupling between Ca<sup>2+...

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Bibliographic Details
Main Authors: Francisco Prista von Bonhorst, David Gall, Geneviève Dupont
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/4/615