Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts
Abstract Background Malignant melanoma of the skin can metastasize through blood vessels and lymphatics. The primary tumor develops a vascular microenvironment characterized by abnormal blood vessels and lymphatics and a physicochemical microenvironment characterized by low oxygen tension, regions w...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12967-017-1307-4 |