Type II collagen-positive progenitors are important stem cells in controlling skeletal development and vascular formation

Abstract Type II collagen-positive (Col2+) cells have been reported as skeletal stem cells (SSCs), but the contribution of Col2+ progenitors to skeletal development both prenatally and postnatally during aging remains unclear. To address this question, we generated new mouse models with ablation of...

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Bibliographic Details
Main Authors: Xinhua Li, Shuting Yang, Gongsheng Yuan, Dian Jing, Ling Qin, Hu Zhao, Shuying Yang
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-022-00214-z