Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults

Objective: Type 2 diabetes mellitus is characterized by metabolic dysregulation in the form of hyperglycemia and insulin resistance and can have a profound impact on brain structure and vasculature. The primary aim of this study was to identify brain regions where the combined effects of type 2 diab...

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Bibliographic Details
Main Authors: Ekaterina Tchistiakova, Nicole D. Anderson, Carol E. Greenwood, Bradley J. MacIntosh
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221315821400076X