<i>PGRMC1</i> Ablation Protects from Energy-Starved Heart Failure by Promoting Fatty Acid/Pyruvate Oxidation

<i>PGRMC1</i> Ablation Protects from Energy-Starved Heart Failure by Promoting Fatty Acid/Pyruvate Oxidation

Heart failure (HF) is an emerging epidemic with a high mortality rate. Apart from conventional treatment methods, such as surgery or use of vasodilation drugs, metabolic therapy has been suggested as a new therapeutic strategy. The heart relies on fatty acid oxidation and glucose (pyruvate) oxidatio...

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Bibliographic Details
Main Authors: Sang R. Lee, Moeka Mukae, Kang Joo Jeong, Se Hee Park, Hi Jo Shin, Sang Woon Kim, Young Suk Won, Hyo-Jung Kwun, In-Jeoung Baek, Eui-Ju Hong
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
<i>Pgrmc1</i>
heart
starvation
ischemia
metabolism
Online Access:https://www.mdpi.com/2073-4409/12/5/752

Internet

https://www.mdpi.com/2073-4409/12/5/752

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