Potential Therapeutics Targeting Upstream Regulators and Interactors of EHMT1/2

Potential Therapeutics Targeting Upstream Regulators and Interactors of EHMT1/2

Euchromatin histone lysine methyltransferases (EHMTs) are epigenetic regulators responsible for silencing gene transcription by catalyzing H3K9 dimethylation. Dysregulation of EHMT1/2 has been reported in multiple cancers and is associated with poor clinical outcomes. Although substantial insights h...

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Bibliographic Details
Main Authors: Gareth Chin Khye Ang, Amogh Gupta, Shirlyn Xue Ling Yap, Uttam Surana, Reshma Taneja
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
lysine methyltransferases
upstream regulators
interactome
post-translational modifications
therapeutics
Online Access:https://www.mdpi.com/2072-6694/14/12/2855

Internet

https://www.mdpi.com/2072-6694/14/12/2855

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