The Antitumor Peptide ERα17p Exerts Anti-Hyperalgesic and Anti-Inflammatory Actions Through GPER in Mice

The Antitumor Peptide ERα17p Exerts Anti-Hyperalgesic and Anti-Inflammatory Actions Through GPER in Mice

Persistent inflammation and persistent pain are major medical, social and economic burdens. As such, related pharmacotherapy needs to be continuously improved. The peptide ERα17p, which originates from a part of the hinge region/AF2 domain of the human estrogen receptor α (ERα), exerts anti-prolifer...

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Bibliographic Details
Main Authors: Christophe Mallet, Ludivine Boudieu, Sylvain Lamoine, Catherine Coudert, Yves Jacquot, Alain Eschalier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
GPER
ERα17p
pain
hyperalgesia
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.578250/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.578250/full

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