Tumor-Infiltrating Lymphocytes (TILs) in Early Breast Cancer Patients: High CD3<sup>+</sup>, CD8<sup>+</sup>, and Immunoscore Are Associated with a Pathological Complete Response

Tumor-Infiltrating Lymphocytes (TILs) in Early Breast Cancer Patients: High CD3<sup>+</sup>, CD8<sup>+</sup>, and Immunoscore Are Associated with a Pathological Complete Response

Background: Tumor-infiltrating lymphocytes are associated with a better prognosis in early triple-negative breast cancer (TNBC). These cells can be enumerated in situ by the “Immunoscore Clinical Research” (ISCR). The original Immunoscore<sup>®</sup> is a prognostic tool that categorizes...

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Bibliographic Details
Main Authors: Bernardo Leon Rapoport, Simon Nayler, Bernhard Mlecnik, Teresa Smit, Liezl Heyman, Isabelle Bouquet, Marine Martel, Jérôme Galon, Carol-Ann Benn, Ronald Anderson
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
CD3<sup>+</sup> lymphocytes
CD8<sup>+</sup> lymphocytes
early breast cancer
HER2-positive breast cancer
Ki-67
luminal breast cancer
Online Access:https://www.mdpi.com/2072-6694/14/10/2525

Internet

https://www.mdpi.com/2072-6694/14/10/2525

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