Epigenetic Dysregulation and Its Correlation with the Steroidogenic Machinery Impacting Breast Pathogenesis: Data Mining and Molecular Insights into Therapeutics

Epigenetic Dysregulation and Its Correlation with the Steroidogenic Machinery Impacting Breast Pathogenesis: Data Mining and Molecular Insights into Therapeutics

Breast cancer (BC) is a heterogeneous condition and comprises molecularly distinct subtypes. An imbalance in the levels of epigenetic histone deacetylases (HDACs), modulating estrogen accumulation, especially 17β-estradiol (E2), promotes breast tumorigenesis. In the present study, analyses of The Ca...

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Bibliographic Details
Main Authors: Pulak R. Manna, Shengping Yang, P. Hemachandra Reddy
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
estrogen/E2
epigenetic enzymes
STAR
steroidogenic machinery
hormone receptors
Online Access:https://www.mdpi.com/1422-0067/24/22/16488

Internet

https://www.mdpi.com/1422-0067/24/22/16488

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