Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Methods to identify protein interaction networks often suffer from poor spatiotemporal resolution. Here the authors present a light-activated proximity labeling method where the protein of interest is fused to the photosensitizer protein miniSOG, allowing temporally resolved labeling of interactors.

Bibliographic Details
Main Authors: Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32689-z

Internet

https://doi.org/10.1038/s41467-022-32689-z

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