Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models

Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models

Abstract Hypertrophic scar formation is influenced by the intricate interplay between fibroblasts and endothelial cells. In this study, we investigated this relationship using in vitro and in vivo models. Clinical observations revealed distinct morphological changes and increased vascularity at path...

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Bibliographic Details
Main Authors: Yaxin Tan, Mengde Zhang, Yi Kong, Fanliang Zhang, Yuzhen Wang, Yuyan Huang, Wei Song, Zhao Li, Linhao Hou, Liting Liang, Xu Guo, Qinghua Liu, Yu Feng, Chao Zhang, Xiaobing Fu, Sha Huang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Bioengineering & Translational Medicine
Subjects:
cell crosstalk
endothelial cell
fibroblast
scar formation
spheroids
Online Access:https://doi.org/10.1002/btm2.10630

Internet

https://doi.org/10.1002/btm2.10630

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