Preservation of general intelligence following traumatic brain injury: contributions of the Met66 brain-derived neurotrophic factor.

Brain-derived neurotrophic factor (BDNF) promotes survival and synaptic plasticity in the human brain. The Val66Met polymorphism of the BDNF gene interferes with intracellular trafficking, packaging, and regulated secretion of this neurotrophin. The human prefrontal cortex (PFC) shows lifelong neuro...

Full description

Bibliographic Details
Main Authors: Aron K Barbey, Roberto Colom, Erick Paul, Chad Forbes, Frank Krueger, David Goldman, Jordan Grafman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0088733&type=printable