GLI3 regulates muscle stem cell entry into GAlert and self-renewal

Primary cilia regulate the processing of the GLI transcription factors and Hedgehog signaling. Here, the authors show that cilia-related GLI3 controls both the quiescence-to-activation transition and self-renewal in muscle stem cells.

Bibliographic Details
Main Authors: Caroline E. Brun, Marie-Claude Sincennes, Alexander Y. T. Lin, Derek Hall, William Jarassier, Peter Feige, Fabien Le Grand, Michael A. Rudnicki
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31695-5