Target Score—A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness

Target Score—A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness

Esophageal cancer (EC) is a life-threatening disease, demanding the discovery of new biomarkers and molecular targets for precision oncology. Aberrantly glycosylated proteins hold tremendous potential towards this objective. In the current study, a series of esophageal squamous cell carcinomas (ESCC...

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Bibliographic Details
Main Authors: Sofia Cotton, Dylan Ferreira, Janine Soares, Andreia Peixoto, Marta Relvas-Santos, Rita Azevedo, Paulina Piairo, Lorena Diéguez, Carlos Palmeira, Luís Lima, André M. N. Silva, Lúcio Lara Santos, José Alexandre Ferreira
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
cancer biomarkers
circulating tumors cells
esophageal cancer
glycomics
glycoproteomics
bioinformatics
Online Access:https://www.mdpi.com/1422-0067/22/4/1664

Internet

https://www.mdpi.com/1422-0067/22/4/1664

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