Unsupervised machine learning method for indirect estimation of reference intervals for chronic kidney disease in the Puerto Rican population

Abstract Reference intervals (RIs) for clinical laboratory values are extremely important for diagnostics and treatment of patients. However, the determination of these ranges is costly and time-consuming. As a result, often different unverified RIs are used in practice for the same analyte and the...

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Bibliographic Details
Main Authors: Julian Velev, Jack LeBien, Abiel Roche-Lima
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43830-3