Carbamazepine regulates USP10 through miR-20a-5p to affect the deubiquitination of SKP2 and inhibit osteogenic differentiation
Abstract Background Antiepileptic drugs (AEDs) harm bone health and are significantly associated with osteoporosis development. In this study, we aimed to explore the mechanisms involved in carbamazepine (CBZ) and microRNA (miR)-20a-5p/ubiquitin-specific peptidase 10 (USP10)/S-phase kinase-associate...
Päätekijät: | , , , , , , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
BMC
2023-11-01
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Sarja: | Journal of Orthopaedic Surgery and Research |
Aiheet: | |
Linkit: | https://doi.org/10.1186/s13018-023-04169-7 |