Construction of cell factory capable of efficiently converting l-tryptophan into 5-hydroxytryptamine

Abstract Background l-Tryptophan (l-Trp) derivatives such as 5-hydroxytryptophan (5-HTP) and 5-hydroxytryptamine (5-HT), N-Acetyl-5-hydroxytryptamine and melatonin are important molecules with pharmaceutical interest. Among, 5-HT is an inhibitory neurotransmitter with proven benefits for treating th...

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Bibliographic Details
Main Authors: Yingying Wang, Xueman Chen, Qiaoyu Chen, Ning Zhou, Xin Wang, Alei Zhang, Kequan Chen, Pingkai Ouyang
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Microbial Cell Factories
Online Access:https://doi.org/10.1186/s12934-022-01745-0