Gene expression based inference of cancer drug sensitivity

Gene expression based inference of cancer drug sensitivity

Predicting treatment response in cancer remains a highly complex task. Here, the authors develop Precily, a deep neural network framework to predict treatment response in cancer by considering gene expression, pathway activity estimates and drug features, and test this method in multiple datasets an...

Full description

Bibliographic Details
Main Authors: Smriti Chawla, Anja Rockstroh, Melanie Lehman, Ellca Ratther, Atishay Jain, Anuneet Anand, Apoorva Gupta, Namrata Bhattacharya, Sarita Poonia, Priyadarshini Rai, Nirjhar Das, Angshul Majumdar, Jayadeva, Gaurav Ahuja, Brett G. Hollier, Colleen C. Nelson, Debarka Sengupta
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33291-z

Internet

https://doi.org/10.1038/s41467-022-33291-z

Similar Items