DNA circles promote yeast ageing in part through stimulating the reorganization of nuclear pore complexes

The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and in many species, it changes composition as the organism ages. However, how these changes arise and whether they contribute themselves to ageing is poorly understood. We show that SAGA-dependent attachment...

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Bibliographic Details
Main Authors: Anne C Meinema, Anna Marzelliusardottir, Mihailo Mirkovic, Théo Aspert, Sung Sik Lee, Gilles Charvin, Yves Barral
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/71196